Which of the following groups is generally prioritized for cervical cancer screening?

Cervical cancer screening is primarily focused on women, specifically those aged 21 to 65, as recommended by the U.S. Preventive Services Task Force. This age group is prioritized because screening has been shown to significantly reduce cervical cancer incidence and mortality. Starting at age 21, regardless of sexual history, women should begin regular screenings for cervical cancer, typically through Pap smears or HPV testing.

The rationale for this specific age range is linked to the natural history of cervical cancer development, which often requires many years to progress from pre-cancerous changes to invasive cancer. Therefore, screening younger individuals who are at lower risk, specifically those under 21, is not routine practice as cervical cancer is uncommon in this age group. Women aged 65 and older who have had adequate prior screenings and are not at high risk may also discontinue screening, although their health circumstances may vary.

Thus, focusing on women aged 21 to 65 optimizes public health efforts by targeting the population most likely to benefit from screening interventions, effectively reducing both the incidence and mortality of cervical cancer in this demographic.